Blog
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Am I statin eligible under the 2026 guideline? How to run your own numbers
The new risk calculator scores most people lower than the old one, and eligibility still went up by 21.5 million. The reason is a second clock nobody was running before.
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Can you lower Lp(a)? The drugs in trials, and why none is approved yet
For years the only advice on a high Lp(a) was to drive every other risk factor down, because nothing touched the number itself. Five drugs are about to change that, and the first real test of whether it matters has not reported yet.
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Can a smartwatch measure blood pressure? What the 2025 guideline says
A wrist reading that appears with no cuff and no ritual is the number everyone wants. It is also the one the 2025 guideline tells you not to rely on, and the reason is measurement, not brand.
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Nattokinase bleeding risk: aspirin, blood thinners, and surgery
The same fibrinolytic action that makes nattokinase interesting is what puts people in the emergency room. Two case reports, both fatal-adjacent, show the two ways it goes wrong.
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Does TRT raise blood pressure? What the FDA label change means
The heart risk on testosterone was not erased, it was made specific. The FDA moved it from a boxed warning nobody could act on to a number you can measure at home for the price of a cuff.
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The rapamycin reversal: why the longevity crowd is backing off
The best-evidenced longevity drug in mice had its confidence knocked in 2024 and 2025. A null human trial, an epigenetic warning sign, and one very public quit.
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Supplement evidence tiers: from S-tier to one rat study
Creatine has hundreds of human trials. Fadogia agrestis has one 2005 rat study and a toxicity signal. Pricing your confidence to the evidence tier is the whole skill.
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What epigenetic clocks actually measure (DunedinPACE vs GrimAge vs PhenoAge)
Three popular clocks give three different answers because they were trained on three different things. One measures mortality risk, one measures your rate of aging, and a single reading is noisier than the marketing admits.
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Creatine for the brain, not just the biceps
The most studied supplement in the world has a second job most people never use it for, and getting it needs a bigger dose than the tub label suggests.
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How to keep muscle while losing fat on a GLP-1
The drug does not target muscle, the speed does. What actually protects lean mass on a GLP-1, and why how you dose it is part of the answer.
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ApoB and Lp(a): what a normal cholesterol panel misses
A cholesterol panel can call you fine while the number that actually drives plaque sits unmeasured. Two markers, one of them a single lifetime test, fix that.
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Body recomp when the scale won't move: what to track instead
A flat weight during a recomp can be the best month of the year or a quietly bad one. The scale cannot tell you which. The tape can.
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How often to retest bloodwork: a cadence per marker class
Each marker has an equilibration time. Draw before it settles and you are measuring the transient, not the new baseline. Here is the cadence that fits the biology.
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The low-effort changes worth trying first (ranked by evidence)
Most easy-wins lists rank by what sounds exciting or what the author is selling. Ranked by evidence, the top of the list is boring behavior, not a supplement.
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Nattokinase and arterial plaque: what the evidence supports
A soybean enzyme with one genuinely striking plaque study, a modest blood pressure effect, and a bleeding risk nobody mentions. What holds up and what does not.
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How to decide which supplements to drop (subtraction as discipline)
What you stopped taking teaches you more than what you take. The subtraction test, and why a bloated stack quietly corrupts your own bloodwork.
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Why a health protocol should take a year, not a weekend
Biology runs on slow clocks. A year gives you four full cycles of measure, intervene, retest, adjust. Here is the rhythm that turns tracking into change.
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Optimal vs normal blood test ranges (and why they differ)
Normal means inside the middle 95% of a reference population. It does not mean fine, and optimal is a different question entirely. Here is how to read both.
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Morning blood pressure surge: the spike your monitor records but never flags
Your monitor has the readings to compute your morning surge. It never does the subtraction. Here is the number, and how to catch your own.
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How to measure blood pressure at home so the numbers mean something
A validated cuff is accurate to a few mmHg. The fifteen seconds before you press start is where the error comes from. Here is the technique that removes it.